Current status and future prospects of p38α/MAPK14 kinase and its inhibitors
… characteristics of p38α, its relationship to the fore-mentioned disease states, … An additional
evidence supporting this finding is that p38α can negatively … Compound 6 (CBS-3595, Fig. …
evidence supporting this finding is that p38α can negatively … Compound 6 (CBS-3595, Fig. …
Synthesis and evaluation of ursolic acid-based 1, 2, 4-triazolo [1, 5-a] pyrimidines derivatives as anti-inflammatory agents
TY Zhang, CS Li, P Li, XQ Bai, SY Guo, Y Jin… - Molecular Diversity, 2022 - Springer
… Here, two series of novel ursolic acid-based 1,2,4-triazolo[1,5… anti-inflammatory activity by
evaluating their inhibition effect of … agents for the treatment of inflammatory diseases [22]. In …
evaluating their inhibition effect of … agents for the treatment of inflammatory diseases [22]. In …
Rottlerin ameliorates DSS-induced colitis by improving intestinal barrier function via activation of the Epac-2/Rap-1 signaling pathway
X Song, L Zuo, L Wang, Z Zhu, J Tao, Y Jiang, X Wu… - bioRxiv, 2020 - biorxiv.org
… Nevertheless, the function of rottlerin on Crohn disease (CD) … Among PDEs, PDE-4 is thought
to inhibit a variety of … our research, and we discovered that rottlerin treatment reduced the …
to inhibit a variety of … our research, and we discovered that rottlerin treatment reduced the …
Phosphodiesterases, 3', 5'-cyclic nucleotide (PDEs) in GtoPdb v. 2023.1
C Yan - IUPHAR/BPS Guide to Pharmacology CITE, 2023 - journals.ed.ac.uk
… 4 inhibitors in inflammatory lung diseases: dual-selective phosphodiesterase … Discovery
of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4…
of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4…
Phosphodiesterases, 3', 5'-cyclic nucleotide (PDEs) in GtoPdb v. 2021.3
C Yan - IUPHAR/BPS Guide to Pharmacology CITE, 2021 - journals.ed.ac.uk
… 4 inhibitors in inflammatory lung diseases: dual-selective phosphodiesterase … Discovery
of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4…
of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4…
Phosphodiesterases, 3', 5'-cyclic nucleotide (PDEs)(version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
C Yan - IUPHAR/BPS Guide to Pharmacology CITE, 2019 - journals.ed.ac.uk
… (2017) Discovery of N-{4-[5-(4-Fluorophenyl)-3-methyl-2methylsulfanyl-… -4-yl]-pyridin-2-yl}-acetamide
(CBS-3595), a Dual p38α MAPK/PDE-4 Inhibitor with Activity against TNFα-Related …
(CBS-3595), a Dual p38α MAPK/PDE-4 Inhibitor with Activity against TNFα-Related …